2025
_MEDICINE Neurology

_Gone Mental

Understanding the brain’s wandering mind is a step toward improving mental health treatments.

_Aaron Kucyi

Kucyi is an assistant professor in the College of Arts and Sciences and director of the Dynamic Brain and Mind Lab.

Our minds wander between 30% and 50% of the time that we’re awake, and neuroscientists are questioning what that indicates about our state of mind. Aaron Kucyi, an assistant professor in Drexel’s College of Arts and Sciences and director of the Dynamic Brain and Mind Lab, published a review with a team of experts in Nature Mental Health summarizing recent advances in understanding how the brain represents spontaneous thought and its impact on mental health.

The review confirmed a growing interest among scientists and clinicians in the practical relevance of mind wandering to mental health. The researchers examined how spontaneous thoughts depend on a person’s mental health status and affect brain function.

Different brain networks support healthy thoughts, like planning and creativity, versus unhealthy thoughts, such as rumination and worry. Emerging research also links the brain’s memory system to spontaneous thought.

“There is excitement around this topic because if we can better understand how these processes work in the brain, then targeted interventions could be designed that may prevent unwanted patterns of thought or guide thoughts toward a healthy direction,” says Kucyi. Kucyi’s lab is using brain imaging tools like EEG and fMRI to develop person-specific mappings between brain networks and spontaneous experiences.

Future research aims to clarify what constitutes healthy versus unhealthy thought patterns and how these are expressed in the brain. This could be key to understanding the variability in human thought processes, paving the way for personalized mental health treatments based on individual brain activity patterns.